Speaker: Crystal T. Clark, M.D., M.Sc.

Title: Personalized Treatment for Bipolar Disorder in Pregnancy: A Pharmacokinetic Perspective

Introduction:
Dr. Crystal Clark is an internationally recognized psychiatrist in women’s mental health. She holds a Canada Research Chair in Reproductive Mental Health. She is an Associate Professor in the Department of Psychiatry at the University of Toronto, and the Associate Head of Research at Women’s College Hospital. Dr. Clark specializes in mood and anxiety disorders specifically across the reproductive life span (from menstruation to peri and post menopause). Dr. Clark’s research has focused on psychopharmacology for the treatment of perinatal mood disorders. Her research aims to prevent the recurrence of illness during pregnancy and postpartum through safe dose optimization and personalized dosing strategies. Her research also aims to develop identification and prevention strategies for all persons with perinatal mood and anxiety disorders including those who are disproportionately impacted by these disorders. Dr. Clark’s research has been funded by the Canadian Institutes of Health Research and the National Institutes of Health. Among Dr. Clark’s many leadership roles, she is a past president of the Marcé of North America, an organization dedicated to advancing perinatal mental health care, and she serves on the board of directors of Marcé International. She has been a contributor to large initiatives in Canada and the US to improve perinatal mental health in North America. Dr. Clark is a thought leader and has been a contributor by several media outlets including CBS, NPR, NY Times, and Chicago Tonight regarding issues related to perinatal mental health.

Learning Objectives
Upon completion of this activity, participants should be able to:

1. Describe pregnancy related physiological challenges that impact the metabolism of 
psychotropics during pregnancy
2. Describe alterations in metabolic pathways due to pregnancy related physiological changes 
and the impact on psychotropic efficacy and clinical management of bipolar disorder
3. Explain clinical approaches to management of bipolar disorder for psychotropics based on 
changes in metabolism during pregnancy

ATTENDANCE / CREDIT
Text the session code (provided only at the session) to 507-200-3010 within 48 hours of the live presentation to record attendance. All learners are encouraged to text attendance regardless of credit needs. This number is only used for receiving text messages related to tracking attendance. Additional tasks to obtain credit may be required based on the specific activity requirements and will be announced accordingly. Swiping your badge will not provide credit; that process is only applicable to meet GME requirements for Residents & Fellows.

TRANSCRIPT
Any credit or attendance awarded from this session will appear on your Transcript.

For disclosure information regarding Mayo Clinic School of Continuous Professional Development accreditation review committee member(s) and staff, please go here to review disclosures.