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Forward27th Annual Mayo Clinic Internal Medicine Update
This course offers Live (in-person) and Livestream (virtual) attendance options
Session I: October 16-19, 2025
LIVE (in person) – Almost Sold Out!
LIVESTREAM (virtual)
Session II: October 30-November 2, 2025
LIVE (in person)
LIVESTREAM (virtual)
Course Directors: Kellie K. Kruger, M.D. and Nathan L. Delafield, M.D.
October 16 - 19 and October 30 - November 2, 2025 - Hilton Sedona Resort - Sedona, Arizona
This annual, four-day course provides primary care practitioners a practical update on topics within the realm of internal medicine and its subspecialties with emphasis on equipping participants with information they can readily incorporate into their practice to improve quality of care and patient outcomes. The popularity of this course is in large part due to the variety of topics presented, many of which are derived from prior participant suggestions, recent advances in medicine and paradigm shifts in medicine. This course also devotes ample time to questions from the audience. ABIM MOC is offered for this activity.
This course has two sessions: October 16 - 19 and October 30-November 2, 2025. While the same 30-minute presentation topics are included for both sessions, the faculty and order of presentations may vary. In addition to the didactic format for lectures, the program includes two daily question-and-answer sessions; and audience participation is encouraged through the use of Vevox.
Session 1: October 16 - 19, 2025 - LIVE Attendance - Almost Sold Out!
Session 2: October 30 - November 2, 2025.
| Registration Fees | Live & Livestream |
|---|---|
| M.D., D.O., Ph.D. | $975 |
| Allied Health, NP, PA, Nurses, Pharmacists, Residents, Retirees | $900 |
*There will be no recordings available post-course*
Target Audience
This course is designed for primary care providers including physicians, nurse practitioners, physician assistants, nurses, pharmacists, and allied health professionals.
Learning Objectives
Upon completion of this activity, participants should be able to:
- Evaluate the latest evidence-based guidelines for the use of non-statin therapies in patients at high cardiovascular risk.
- Identify digital health technologies, such as ambient listening, and their use in patient care.
- Cite the principles of CAR T-cell therapy.
- Describe evidence-based strategies for screening for various substance use disorders in a primary care setting.
- Recognize common conditions affecting veterans, including post-traumatic stress disorder (PTSD) and toxic exposure-related illnesses.
- Recognize the emerging role of multi-cancer early detection (MCED) tests in primary care.
- Review available treatment options for Alzheimer’s Disease (AD).
- Describe the role of amyloid-directed therapies in the treatment of AD.
Attendance at any Mayo Clinic course does not indicate or guarantee competence or proficiency in the skills, knowledge or performance of any care or procedure(s) which may be discussed or taught in this course.
Session 1: October 16-19, 2025
27th Annual Mayo Clinic Internal Medicine Update |
Sedona, AZ |
October 16 - October 19, 2025 |
All Presentations Mountain Standard Time |
| ACPE UAN number is UAN JA0000238-0000-25-115-L01-P |
Thursday, October 16, 2025 | |
6:00 AM | Registration, Breakfast and Exhibits |
7:15 AM | Welcome Announcements |
7:30 AM | Collaborative Practice Agreements in Primary Care |
8:00 AM | Multi-Cancer Detection (MCD) for Primary Care |
8:30 AM | Low T and Who to Treat |
9:00 AM | Q&A |
9:30 AM | Refreshment Break and Exhibits |
10:00 AM | Listening Beyond the Stethoscope: Humanities as a Compass for Care and Quality |
10:30 AM | Updates in Anticoagulation for Primary Care- Managing Tough Cases |
11:00 AM | Updates in Addiction Medicine for Primary Care |
11:30 AM | Veterans’ Medicine in Primary Care |
12:00 PM | Q&A |
12:30 PM | Adjourn |
| 12:40 PM - 1:30 PM | Optional: Non-CME Product Theater Lunch |
| 5:30 PM | Welcome Reception |
Friday, October 17, 2025 | |
6:00 AM | Breakfast and Exhibits |
7:15 AM | Announcements |
7:30 AM | Challenges and Solutions in the Era of GLP-1s |
8:00 AM | Updates in Perioperative Medicine for Primary Care |
8:30 AM | Integrated Behavioral Health and Why It Works in Primary Care |
9:00 AM | Q&A |
9:30 AM | Refreshment Break and Exhibits |
10:00 AM | Non-Hormonal Treatments for Menopausal Symptoms |
10:30 AM | CAR T-Cell Therapy for Primary Care |
11:00 AM | Updates in Valley Fever, Diagnosis and Management |
11:30 AM | Hyponatremia – When to Worry? |
12:00 PM | Q&A |
12:30 PM | Adjourn |
Saturday, October 18, 2025 | |
6:00 AM | Registration, Breakfast and Exhibits |
7:15 AM | Announcements |
7:30 AM | Updates in Palliative Medicine for Primary Care |
8:00 AM | Updates in Pulmonary Medicine |
8:30 AM | Updates in Parkinson’s Disease and Tremor |
9:00 AM | Q&A |
9:30 AM | Refreshment Break and Exhibits |
10:00 AM | Managing Non-Operative MSK Injuries in Primary Care |
10:30 AM | Beyond Statins: Advanced Lipid Lowering Therapy for Primary Care |
11:00 AM | REM Sleep Behavior Disorder |
11:30 AM | Updates in Dementia Treatment and Prevention for Primary Care |
12:00 PM | Q&A |
12:30 PM | Adjourn |
Sunday, October 19, 2025 | |
6:00 AM | Registration, Breakfast and Exhibits |
7:15 AM | Announcements |
7:30 AM | Updates in Drug Allergy Testing for Primary Care |
8:00 AM | GLP1 Medications for Cardiovascular Disease |
8:30 AM | Spondyloarthropathies for Primary Care |
9:00 AM | Q&A |
9:30 AM | Refreshment Break and Exhibits |
10:00 AM | Updates in Hepatitis Management |
10:30 AM | Primary Care After Bone Marrow Transplant |
11:00 AM | Artificial Intelligence and Emerging Technologies in Medicine, for Primary Care |
11:30 AM | Q&A |
12:00 PM | Adjourn |
Session 2: October 30-November 2, 2025
27th Annual Mayo Clinic Internal Medicine Update |
Sedona, AZ |
October 30 – November 2, 2025 |
All Presentations Mountain Standard Time |
| ACPE UAN number is UAN JA0000238-0000-25-116-L01-P |
Thursday, October 30, 2025 | |
6:00 AM | Registration, Breakfast and Exhibits |
7:15 AM | Welcome Announcements |
7:30 AM | Updates in Hepatitis Management |
8:00 AM | Non-Hormonal Treatments for Menopausal Symptoms |
8:30 AM | Updates in Drug Allergy Testing for Primary Care |
9:00 AM | Q&A |
9:30 AM | Refreshment Break and Exhibits |
10:00 AM | Managing Non-Operative MSK Injuries in Primary Care |
10:30 AM | Veterans’ Medicine in Primary Care |
11:00 AM | Updates in Parkinson’s Disease and Tremor |
11:30 AM | REM Sleep Behavior Disorder |
12:00 PM | Q&A |
12:30 PM | Adjourn |
| 12:30 PM - 1:30 PM | Optional: Non-CME Product Theater Lunch |
| 5:30 PM | Welcome Reception |
Friday, October 31, 2025 | |
6:00 AM | Breakfast and Exhibits |
7:15 AM | Announcements |
7:30 AM | Updates in Pulmonary Medicine |
8:00 AM | Updates in Valley Fever; Diagnosis and Management |
8:30 AM | Spondyloarthropathies for Primary Care |
9:00 AM | Q&A |
9:30 AM | Refreshment Break and Exhibits |
10:00 AM | Primary Care After Bone Marrow Transplant |
10:30 AM | Multi-Cancer Detection (MCD) for Primary Care |
11:00 AM | Collaborative Practice Agreements in Primary Care |
11:30 AM | Updates in Anticoagulation for Primary Care- Managing Tough Cases |
12:00 PM | Q&A |
12:30 PM | Adjourn |
Saturday, November 1, 2025 | |
6:00 AM | Registration, Breakfast and Exhibits |
7:15 AM | Announcements |
7:30 AM | Updates in Addiction Medicine, for Primary Care |
8:00 AM | Updates in Palliative Medicine for Primary Care |
8:30 AM | Updates in Dementia Treatment and Prevention for Primary Care |
9:00 AM | Q&A |
9:30 AM | Refreshment Break and Exhibits |
10:00 AM | Listening Beyond the Stethoscope: Humanities as a Compass for Care and Quality |
10:30 AM | GLP1 Medications for Cardiovascular Disease |
11:00 AM | Challenges and Solutions in the Era of GLP-1s |
11:30 AM | Hyponatremia – When to Worry? |
12:00 PM | Q&A |
12:30 PM | Adjourn |
Sunday, November 2, 2025 | |
6:00 AM | Registration, Breakfast and Exhibits |
7:15 AM | Announcements |
7:30 AM | Beyond Statins: Advanced Lipid Lowering Therapy for Primary Care |
8:00 AM | Integrated Behavioral Health and Why It Works in Primary Care |
8:30 AM | Artificial Intelligence and Emerging Technologies in Medicine, for Primary Care |
9:00 AM | Q&A |
9:30 AM | Refreshment Break and Exhibits |
10:00 AM | Low T and Who to Treat |
10:30 AM | Updates in Perioperative Medicine for Primary Care |
11:00 AM | CAR T-Cell Therapy for Primary Care |
11:30 AM | Q&A |
12:00 PM | Adjourn |
***PLEASE NOTE: Session I Room Block is Sold Out – Session I (October 16-19, 2025)***
Hilton Sedona Resort
90 Ridge Trail Drive
Sedona, AZ 86351
Phone: 877-273-3762
A block of guest suites has been reserved at a special group rate of $299 (USD) for deluxe rooms or $319 (USD) for suites, per night, plus a $20 daily resort fee and applicable state/local taxes. To receive the special group rate, please identify yourself as a registrant of the 27th Annual Mayo Clinic Internal Medicine Update and make your reservation before the room block is filled or by the expiration date (Session II: September 29, 2025). You may reserve your room online or call the hotel directly at 877-273-3762.
Attendees are responsible for their own reservations. The standard hotel reservation cancellation policy will apply to individual reservations unless otherwise specified.
Reservation Links:
First Session: October 16 - 19, 2025 - ROOM BLOCK SOLD OUT
Second Session: October 30 - November 2, 2025
We apologize, but due to high interest in the 27th Annual Mayo Clinic Internal Medicine Update - Session 1 (October 16-19), the room block has sold out at the Hilton Sedona Resort. To sign up for the waitlist, please contact the resort at 877-273-3762 to be notified if guest suites become available.
ALTERNATIVE HOTEL ACCOMMODATIONS
Lodging arrangements are the sole responsibility of the individual registrant.
| Hotel | Distance to Hilton Sedona |
|---|---|
Element Sedona | Approximately 0.6 miles, or 2 minutes |
Holiday Inn Express Sedona – Oak Creek | Approximately 1.5 miles, or 4 minutes |
Bell Rock Inn | Approximately 1.5 miles, or 4 minutes |
Travel
AIRPORTS
Phoenix Sky Harbor International Airport PHX) – 112 miles or approximately one hour, 45 minutes to hotel.
The Hilton Sedona Resort is located about two hours north of Phoenix. Temperatures average 20 degrees cooler than the Phoenix area in the summer.
Visit www.visitsedona.com for recreation and leisure activities in the Sedona area.
Course Directors
Nathan L. Delafield, M.D.
Kellie K. Kruger, M.D.
Mayo Faculty
Abeer M. AlMajali, M.D.
Neera Agrwal, M.D., Ph.D.
David M.H. Chascsa, M.D.
Shannon Y. Chiu, M.D.
Angela N. Coulter, Pharm.D., R.Ph.
Callie M. Davies, M.D.
Mark K. Edwin, M.D.
Claudine J. Egol, M.D.
Regis I. Fernandes, M.D.
Brian W. Hardaway, M.D.
Richard A. Helmers, M.D.
Talal Hilal, M.D.
Musab S. Hommos, M.B.B.S.
Susan A. Kinate, P.A.-C., M.S.
Katherine C. Kough
Nolan K. Mc Bride, M.D.
Sneha Mishra, M.B.B.S.
Chance J. Moyer, P.A.-C., M.S.
Nahid Punjani, M.D., M.P.H.
Steven W. Ressler, M.D.
Kevin C. Ruff, M.D.
Fadi E. Shamoun, M.D.
Shirshendu Sinha, M.B.B.S., M.D.
Talia Sobel, M.D.
Yasemin S. Tashman, M.D.
Terrence L. Trentman, M.D.
Bryan K. Woodruff, M.D.
Udit Yadav, M.B.B.S.
Accreditation Statement
In support of improving patient care, Mayo Clinic College of Medicine and Science is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.
Credit Statement(s):
AMA
Mayo Clinic College of Medicine and Science designates this live activity for a maximum of 17.50 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
AAPA
Mayo Clinic College of Medicine and Science has been authorized by the American Academy of Physician Associates (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 17.50 AAPA Category 1 CME credits. PAs should only claim credit commensurate with the extent of their participation.
ACPE
Mayo Clinic College of Medicine and Science designates this educational activity for a maximum of 17.50 ACPE Knowledge-based contact hours. Participants should claim only the credit commensurate with the extent of their participation in the activity.
UAN Number:
Session 1: UAN JA0000238-0000-25-115-L01-P
Session 2: UAN JA0000238-0000-25-116-L01-P
ANCC
Mayo Clinic College of Medicine and Science designates this activity for a maximum of 17.50 ANCC contact hours. Nurses should claim only the credit commensurate with the extent of their participation in the activity.
AAFP
The AAFP has reviewed 27th Annual Mayo Clinic Internal Medicine Update, and deemed it acceptable for AAFP credit. Term of approval is from 10/16/2025 to 10/15/2026. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
This session is approved for 17.50 live AAFP Prescribed credits.
AAFP Prescribed credit is accepted by the American Medical Association as equivalent to AMA PRA Category 1 credit(s)™ toward the AMA Physician's Recognition Award. When applying for the AMA PRA, Prescribed credit earned must be reported as Prescribed, not as Category 1.
AOA
The American Osteopathic Association designates this program for a maximum of 17.50 AOA Category 2-A credits.
ACHE
By attending the 27th Annual Mayo Clinic Internal Medicine Update offered by Mayo Clinic College of Medicine and Science participants may earn up to 17.50 ACHE Qualifying Education Hours toward initial certification or recertification of the Fellow of the American College of Healthcare Executives (FACHE) designation.
IPCE
This activity was planned by and for the healthcare team, and learners will receive 17.50 Interprofessional Continuing Education (IPCE) credit for learning and change.
American Board of Internal Medicine (ABIM)
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 17.50 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
Royal College of Physicians and Surgeons of Canada
Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.
Other Healthcare Professionals:
A record of attendance will be provided to all registrants for requesting credits in accordance with state nursing boards, specialty societies or other professional associations.
| Day | Credit(s) |
|---|---|
| Thursday | 4.50 |
| Friday | 4.50 |
| Saturday | 4.50 |
| Sunday | 4.00 |
| Total | 17.50 |
For disclosure information regarding Mayo Clinic School of Continuous Professional Development accreditation review committee member(s) and staff, please go here to review disclosures.
Available Credit
- 17.50 AAFP Prescribed
- 17.50 AAPA Category 1
- 17.50 ABIM
- 17.50 ACHE
- 17.50 ACPE
- 17.50 AMA PRA Category 1 Credit™
- 17.50 ANCC
- 17.50 AOA Category 2-A
- 17.50 Attendance
- 17.50 IPCE
Sponsorship and Exhibit Opportunities
This course offers the unique opportunity for a variety of sponsorship opportunities, including the ability to interact with healthcare providers and highlight products and services through an exhibit. The letter of request and sponsorship descriptions can be found here. W-9 attached here. Space is limited and reserved upon receipt of a completed agreement.
If you are interested in sponsoring or exhibiting at the 27th Annual Mayo Clinic Internal Medicine Update, please complete the appropriate Letter of Agreement via the link below. If you do not have a profile/account you will first need to create one before completing the online form.
- If you are interested in participating, please complete the Exhibitor Letter of Agreement.
Contact: Jeanette Arvizu with questions.
Please update your profile to let us know if you have dietary restrictions or access requirements.
To claim credit for livestream participation in this course, learners must view the content during the hours posted for the live/livestream activity. This course is not approved for on-demand delivery and no video recordings will be posted.
Commitment to Belonging and Inclusion
Mayo Clinic School of Continuous Professional Development (MCSCPD) strives to foster a learning environment in which all individuals are valued, allowing all to achieve their fullest potential.
Cancellation and Refund Policy
View Cancellation and Refund Policy
All requests must be submitted in writing using the Contact Us Form.
Any use of this site constitutes your agreement to the Terms and Conditions of Registration.