PRESENTATION TITLE
Mutational Signature 3 from Clinical Sequencing as Predictor of Response to PARPi

PRESENTER(S)
Felipe Batalini Freitas Silva, M.D., Assistant Professor of Medicine, in the Department of Medical Oncology, Mayo Clinic, Phoenix, Arizona

PRESENTER BIO

Felipe Batalini, M.D., is a medical oncologist focused on the treatment of breast and gynecological cancers. He is an Assistant Professor of Oncology in the Mayo Clinic College of Medicine. Dr. Batalini did his Residency in Internal Medical at Boston University Medical Center, and his Fellowship in Hematology and Oncology at Beth Israel Deaconess Medical Center, at Harvard Medical School. He is a member of the American Society of Clinical Oncology (ASCO) and American Association for Cancer Research (AACR). Dr. Batalini is a reviewer of the most prominent oncology journals and leads research in the fields of genetics and genomics, with expertise on precision oncology, liquid biopsies, DNA damage and repair, and the development of new treatments for cancer patients.

Dr. Batalini’s clinical and research focus includes:

• Precision medicine: identifying genetic alterations unique to each patient to guide treatment choices or clinical trial participation.
• Liquid biopsies: studies the incorporation of new technologies to individualize care and bring research findings to patient care.
• DNA damage and repair: development of genomic biomarkers of homologous recombination repair.
• Hereditary cancers: expertise on the treatment of patients with strong family history of cancer or carriers of hereditary mutations of cancer risk genes, including BRCA1, BRCA2, and others.

VIEWING LOCATIONS
Zoom Registration Link

LEARNING OBJECTIVES

• Identify the unmet need in metastatic triple-negative breast cancer.
• Demonstrate strategies to expand indications for PARPi.
• Describe Sig3 and other HRD biomarkers.
• Evaluate Sig3 as a candidate HRD-biomarker.

ATTENDANCE / CREDIT
Text the session code (provided only at the session) to 507-200-3010 within 48 hours of the live presentation to record attendance. All learners are encouraged to text attendance regardless of credit needs. This number is only used for receiving text messages related to tracking attendance. Additional tasks to obtain credit may be required based on the specific activity requirements and will be announced accordingly. Swiping your badge will not provide credit; that process is only applicable to meet GME requirements for Residents & Fellows.

TRANSCRIPT
Any credit or attendance awarded from this session will appear on your Transcript.

For disclosure information regarding Mayo Clinic School of Continuous Professional Development accreditation review committee member(s) and staff, please go here to review disclosures.