Title: Myocardial ribonucleoprotein granulopathy: a new phase in heart failure

Presenter:

Learning Objectives:

1) Appreciate value of modeling human genetic heart disease by germline genome editing in pigs.  

2) Explain concepts of liquid-liquid phase separation biophysics, RBM20 biology and ribonucleoprotein granules in cardiomyocytes.

3) Recognize importance of ribonucleoprotein granule disease across spectrum of human pathobiology from ALS to heart failure

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TRANSCRIPT
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